Proteins

The new TSKgel UP-SW columns, packed with 2 micron silica-based particles, are optimized for the UHPLC analysis of proteins, such as monoclonal antibodies. They are the result of over 40 years of experience in gel filtration technology and provide the same outstanding quality and reproducibility known from the renowned TSKgel SW series.

The TSKgel SW mAb products consist of three specialized columns designed for the analysis of monoclonal antibodies (mAbs). Compared to competitive columns, these stainless steel, silica-based TSKgel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates.

TSKgel SW, SWXL and SuperSW columns are silica-based columns optimized for the separation of proteins and nucleic acids using an aqueous buffer as the mobile phase. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples. Compared to competitive HPLC columns, TSKgel SW-type columns contain more pore volume per unit column volume, which results in higher molar mass (MM) selectivity or better resolution. The columns within the TSKgel SW-type group differ in pore size, offering the ability to separate a wide range of compounds of varying molar mass.